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Absorption and distribution of chitosan in mice after oral administration

Four chitosan samples with different molecular weight Mw and the degree of deacetylation DD (HCS 7.60 · 105 and 85.5%, MCS 3.27 · 104 and 85.2%, COS 0.99 · 103 and 85.7%, WSC 3.91 · 104 and 52.6%) were prepared, and labeled by fluorescein isothiocyanate. These labeled samples were used to investigate the absorption and distribution in mice after oral administration.

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